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New migraine treatment approach: study with 1,000 participants begins

Around 18 million Germans suffer from migraines. A new study involving researchers from Dresden is now looking for better ways to treat them.
Migraines are much more than just headaches - they often paralyze sufferers for hours or days. © pixabay/fairpharma
From: Wissensland
Migraine attacks return several times a month for many patients. Yet millions of people still do not receive treatment tailored to their needs. The MIGRA-MD study aims to change this with a digital, personalised approach. Dresden University Hospital is taking part and is looking for participants from the region.

7 o'clock in the morning. The alarm clock rings. But instead of getting up, the pain tightens again like a vice around your head. Light hurts, sounds too. Anyone who knows migraines knows that this is no ordinary headache. Two out of three adults in Germany suffer from headaches at least some of the time. Around 18 million of them are affected by migraines. Despite this, many do not receive treatment that really suits their situation. A new research project aims to change this. The University Hospital Carl Gustav Carus Dresden is involved in it.

The project is called MIGRA-MD. It is testing a structured treatment for migraine patients that combines various forms of therapy and uses digital aids. Over the next year and a half, 1,000 sufferers across Germany are expected to take part. The project is being funded by the Federal Joint Committee (G-BA) with over five million euros. It is being led by LMU Klinikum München.

"This project with its multimodal approach and use of digital applications has the potential to significantly improve the care of people with migraines," says Prof. Gudrun Goßrau, Head of the Headache Center at Dresden University Hospital.

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How the program works

Participants keep a digital headache diary via a smartphone app from the German Migraine and Headache Society. Doctors can view this data before the appointment and plan treatment in a more targeted manner. There is also an online platform with short videos and audios on migraines, triggers and treatment options, such as stress reduction, relaxation exercises or exercise.

Participation lasts 13 months and includes three personal specialist appointments. Participants are randomly assigned to a group with an immediate or three-month delayed start of treatment. This procedure is called randomization and ensures scientifically reliable results.

Who can participate?

Participation is open to people with statutory health insurance who regularly have between four and 25 headache days per month. In addition, no more than two preventive medications may have been tried so far without success. Patients from the Dresden and East Saxony region can be treated at the Headache Center at Dresden University Hospital. Participants are randomly assigned to a group. One starts treatment immediately, the other only three months later. This procedure is called randomization. It ensures that the results of the study are scientifically reliable.

The Coordination Center for Clinical Trials at TU Dresden is supervising the study. "We are pleased to contribute to good data quality with our work so that meaningful study results can be achieved," says its director Dr. Xina Grählert. If the study shows clear improvements - for example in the frequency of headaches or the stress in everyday life - the new model could be adopted in normal medical care in the future. Many migraine sufferers would benefit from this in the long term.

Further information on the project can be found here.

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